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Publications

  • Gamage ST, Bortolin-Cavaillé ML, Link C, Bryson K, Sas-Chen A, Schwartz S, Cavaillé J, Meier JL. Antisense pairing and SNORD13 structure guide RNA cytidine acetylation. (2022) RNA. rna.079254.122.
     

  • Bortolin-Cavaillé ML, Quillien A, Gamage ST, Thomas JM, Sas-Chen A, Sharma S, Plisson-Chastang C, Vandel L, Blader P, Lafontaine DLJ, Schwartz S, Meier JL, Cavaillé J. Probing small ribosomal subunit RNA helix 45 acetylation across eukaryotic evolution. (2022) Nucleic Acids Research. 50(11):6284-6299.
     

  • Nir R, Hoernes TP, Muramatsu H, Faserl K, Karikó K, Erlacher MD, Sas-Chen A, Schwartz S. A systematic dissection of determinants and consequences of snoRNA-guided pseudouridylation of human mRNA. (2022) Nucleic Acids Research. 50(9):4900-4916. [co-corresponding author]
     

  • Rebelo-Guiomar P, Pellegrino S, Dent KC, Sas-Chen A, Miller-Fleming L, Garone C, Van Haute L, Rogan JF, Dinan A, Firth AE, Andrews B, Whitworth AJ, Schwartz S, Warren AJ, Minczuk M. A late-stage assembly checkpoint of the human mitochondrial ribosome large subunit. (2022) Nature Communications. 13(1):929.
     

  • Begik O*, Lucas MC*, Pryszcz LP, Ramirez JM, Medina R, Milenkovic I, Cruciani S, Liu H, Santos Vieira HG, Sas-Chen A, Mattick JS, Schwartz S and Novoa EM. (2021). Quantitative profiling of native RNA modifications and their dynamics using nanopore sequencing. Nature Biotechnology. doi: 10.1038/s41587-021-00915-6.

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  • Gamage ST*, Sas-Chen A*, Schwartz S, Meier J (2021). Quantitative nucleotide resolution profiling of RNA cytidine acetylation by ac4C-seq. Nature Protocols. 16(4):2286-2307.

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  • Sas-Chen A, Nir R, Schwartz S. (2021). mito-Ψ-Seq: A high-throughput method for systematic mapping of pseudouridine within mitochondrial RNA. Methods in Molecular Biology. 2192:103-115.

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  • Sas-Chen A*, Thomas JM*, Matzov D*, Taoka M, Nance KD, Nir R, Bryson KM, Shachar R, Liman GLS, Burkhart BW, Gamage ST, Nobe Y, Briney CA, Levy MJ, Fuchs RT, Robb GB, Hartmann J, Sharma S, Lin Q, Florens L, Washburn MP, Isobe T, Santangelo TJ, Shalev-Benami M, Meier JL, Schwartz S (2020). Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping. Nature. 583, 638–643.

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  • Sas-Chen A, Schwartz S. (2019). Misincorporation signatures for detecting modifications in mRNA: Not as simple as it sounds. Methods. 1;156:53-59. doi: 10.1016/j.ymeth.2018.10.011.

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  • Thomas JM, Briney CA, Nance KD, Lopez JE, Thorpe AL, Fox SD, Bortolin-Cavaille ML, Sas-Chen A, Arango D, Oberdoerffer S, Cavaille J, Andresson T, Meier JL. (2018). A Chemical Signature for Cytidine Acetylation in RNA. Journal of the American Chemical Society. 140(40):12667-12670. doi: 10.1021/jacs.8b06636.

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  • Roth L, Srivastava S, Lindzen M, Sas-Chen A, Scheffer M, Lauriola M, Enuka Y, Noronha A, Mancini M, Lavi S, Tarcic G, Pines G, Nevo N, Heyman O, Ziv T, Rueda OM, Gnocchi D, Pikarsky E, Admon A, Caldas C, Yarden Y. (2018). SILAC identifies LAD1 as an oncogenic filamin binder regulating actin dynamics in response to EGF and marking aggressive breast tumors. Science Signaling. 11(515). doi: 10.1126/scisignal.aan0949.

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  • Safra M, Sas-Chen A, Nir R, Winkler R, Nachshon A, Bar-Yaacov D, Erlacher M, Rossmanith W, Stern-Ginossar N, Schwartz S. (2017). The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution. Nature. doi:10.1038/nature24456.

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  • Enuka Y, Feldman ME, Chowdhury A, Srivastava S, Lindzen M, Sas-Chen A, Massart R, Cheishvili D, Suderman MJ, Zaltsman Y, Mazza CA, Shukla K, Körner C, Furth N, Lauriola M, Oren M, Wiemann S, Szyf M, Yarden Y. (2017). Epigenetic mechanisms underlie the crosstalk between growth factors and a steroid hormone. Nucleic Acids Research. doi: 10.1093/nar/gkx865.

  • Sas-Chen A, Srivastava S, Yarden Y (2017). The short and the long: Non-coding RNAs and growth factors in cancer progression. Biochemical Society Transactions. 8;45(1):51-64.

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  • Sas‐Chen A,  Aure MR,  Leibovich L,  Carvalho S,  Enuka Y,  Körner C,  Polycarpou‐Schwarz M,  Lavi S,  Nevo N,  Kuznetsov Y,  Yuan J,  Azuaje F,  Oslo Breast Cancer Research Consortium (OSBREAC),  Ulitsky I,  Diederichs S,  Wiemann S,  Yakhini Z,  Kristensen VN,  Børresen‐Dale AL,  Yarden Y. (2016). LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer. EMBO Molecular Medicine. pii: e201606198.

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  • Enuka Y, Lauriola M, Feldman ME, Sas-Chen A, Ulitsky I, Yarden Y (2016). Circular RNAs are long-lived and display only minimal early alterations in response to a growth factor. Nucleic Acids Research. pii: gkv1367.

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  • Kedmi M, Sas-Chen A, Yarden Y (2015). MicroRNAs and Growth Factors: An Alliance Propelling Tumor Progression. Journal of Clinical Medicine. 4(8):1578-99.

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  • Blandino G, Fazi F, Donzelli S, Kedmi M, Sas-Chen A, Muti P, Strano S, Yarden Y. (2014). Tumor suppressor microRNAs: a novel non-coding alliance against cancer. FEBS Letters. 588(16):2639-52.

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  • Sas-Chen A, Avraham R, Yarden Y. (2012). A crossroad of microRNAs and immediate early genes (IEGs) encoding oncogenic transcription factors in breast cancer. Journal of Mammary Gland Biology and Neoplasia. 17(1):3-14.

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  • Zwang Y, Sas-Chen A, Drier Y, Shay T, Avraham R, Lauriola M, Shema E, Lidor-Nili E, Jacob-Hirsch J, Amariglio N, Lu Y, Mills GB, Rechavi G, Oren M, Domany E, Yarden Y. (2011). Two phases of mitogenic signaling unveil roles for p53 and EGR1 in elimination of inconsistent growth signals. Molecular Cell.  42(4):524-35.

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  • Avraham R, Sas-Chen A, Manor O, Steinfeld I, Shalgi R, Tarcic G, Bossel N, Zeisel A, Amit I, Zwang Y, Enerly E, Russnes HG, Biagioni F, Mottolese M, Strano S, Blandino G, Børresen-Dale AL, Pilpel Y, Yakhini Z, Segal E, Yarden Y. (2010). EGF decreases the abundance of microRNAs that restrain oncogenic transcription factors. Science Signaling. , 3(124):ra43.

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  • Kaushansky N, Zilkha-Falb R, Hemo R, Lassman H, Eisenstein M, Sas A, Ben-Nun A. (2007). Pathogenic T cells in MOBP-induced murine EAE are predominantly focused to recognition of MOBP21F and MOBP27P epitopic residues. European Journal of Immunology. 37(11):3281-92.

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  • Ben-Ari S, Toiber D, Sas AS, Soreq H & Ben-Shaul Y (2006). Modulated splicing-associated gene expression in P19 cells expressing distinct acetylcholinesterase splice variants. Journal of Neurochemistry, 97 (s1), 24-34.

For the full list of publications

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